Publications

On this page only the publications of the last 3 years are displayed.
Earlier publications can be found here: to the complete list.

Year of publication: 2020
Authors Title Journal Link
Grill S, Ring A, Brannath W, Scharpenberg M Assessing consistency in clinical trials with two subgroups and binary endpoints: A new test within the logistic regression model. Statistics in Medicine
Jilani H, Rathjen K I, Schilling I, Herbon C, Scharpenberg M, Brannath W, Gerhardus A Handreichung zur Patient*innenbeteiligung an klinischer Forschung, Version 1.0 Universität Bremen
Rathjen K I, Herbon C, Jilani H, Scharpenberg M, Schilling I, Schmiemann G, Brannath W, Gerhardus A Aktive Beteiligung von älteren Patient*innen an klinischer Forschung (INVOLVE-Clin): Ein Studienprotokoll. ZEFQ
Mirastschijski U, Schwab I, Coger V, Zier U, Rianna C, He W, Maedler K, Kelm S, Radtke A, Belge G, Lindner P, Stahl F, Scharpenberg M, Lasota L, Timm J Lung Surfactant Accelerates Skin Wound Healing: A Translational Study with a Randomized Clinical Phase I Study Sci Rep 10, 2581
Year of publication: 2019
Authors Title Journal Link
Czwikla, J., Schulz, M., Heinze, F., Kalwitzki, F., Gand, D., Schmidt, A., Tsiasioti, C., Schwinger, A., Kloep, S., Schmiemann, G., Wolf-Ostermann, K., Gerhardus, A., Rothgang, H. Needs-based provision of medical care to nursing home residents in Germany: protocol of a mixed-methods study. BMJ Open; 9:e025614
Veselinović T, Scharpenberg M, Heinze M, Cordes J, Mühlbauer B, Juckel G, Habel U, Rüther E, Timm J, Gründer G Disparate effects of first and second generation antipsychotics on cognition in schizophrenia - Findings from the randomized NeSSy trial Eur Neuropsychopharmacol Volume 29, Issue 6, pp. 720-739
Veselinović T, Scharpenberg M, Heinze M, Cordes J, Mühlbauer B, Juckel G, Rüther E, Paulzen M, Haen E, Hiemke C, Timm J, Gründer G Dopamine D2 Receptor Occupancy Estimated From Plasma Concentrations of Four Different Antipsychotics and the Subjective Experience of Physical and Mental Well-Being in Schizophrenia: Results From the Randomized NeSSy Trial J Clin Psychopharmacol. Volume 39, Issue 6, pp. 550-560
Year of publication: 2018
Authors Title Journal Link
Vradi E, Brannath W, Jaki T, Vonk R Model selection based on combined penalties for biomarker identification Journal of Biopharmaceutical Statistics, 28(4):735-749 (doi: 10.1080/10543406.2017.1378662)
Awad D, Wili´nska J, Gousia D, Shi X, Eddous J, Müller A, Wagner V, Hillner C, Brannath W, Mohr A, Gabel D Toxicity and phototoxicity in human ARPE-19 retinal pigment epithelium cells of dyes commonly used in retinal surgery European Journal of Ophthalmology, 28(4):433-440 (doi: 10.1177/1120672118766446)
Rauch G, Brannath W, Brückner M, Kieser M The Average Hazard Ratio - A Good Effect Measure for Time-to-event Endpoints when the Proportional Hazard Assumption is Violated? Methods of Information in Medicine, 57(3):89-100 (doi: 10.3414/ME17-01-0058)
Jaki T, Gordon A, Bijnens L, Bornkamp B, Brannath W, Fontana R, Gasparini M, Hampson LV, Jacobs T, Jones B, Paoletti X, Posch M, Titman A, Vonk R, Koenig F A proposal for a new PhD level curriculum on quantitative methods for drug development Pharmaceutical Statistics, 1-14
Nhacolo A, Brannath W Interval and point estimation in adaptive Phase II trials with binary endpoint Statistical Methods in Medical Research, published online
Vradi E, Jaki T, Vonk R, Brannath W A Bayesian model to estimate the cutoff and the clinical utility of a biomarker assay Statistical Methods in Medical Research, pulished online (doi: 10.1177/0962280218784778)
Ring A, Scharpenberg M, Grill S, Schall R, Brannath W Equivalence Tests in Subgroup Analyses New Frontiers of Biostatistics and Bioinformatics/ (pp. 201-238)
Saha S, Brannath W Comparison of different approaches for dose response analysis Biometrical Journal, to appear (doi: 10.1002/bimj.201700276)
Brückner M, Burger U, Brannath W Non-parametric adaptive enrichment designs using categorical surrogate data Statistics in Medicine, to appear
Year of publication: 2017
Authors Title Journal Link
Zierk J, Arzideh F, Haeckel R, Cario H, Frühwald M, Gro H.J, Gscheidmeier T, Hoffmann R, Krebs A, Lichtinghagen R, Neumann M, Ruf H.G, Steigerwald U, Streichert T, Rascher W, Metzler M, Rauh M Pediatric reference intervals for alkaline phosphatase Clin Chem Lab Med; 55(1): 102-110 (2017)
Bauer A, Hausmann H, Schaarschmidt J, Scharpenberg M, Troitzsch D, Johansen P, Nygaard H, Eberle T, Hasenkam J M Shed-blood-separation and cell-saver: an integral Part of MiECC? Shed-blood-separation and ints influence on the perioperative inflammatory response during coronary revascularization with minimal invasive extracorporeal ciculation systems - a randomized c Perfusion. Vol 33, Issue 2, pp. 136 - 147 First Published September 22, 2017
Bauer A, Hausmann H, Schaarschmidt J, Szlapka M, Scharpenberg M, Eberle T, Hasenkam J M Is 300 Seconds ACT Safe and Efficient during MiECC Procedures? DOI:10.1055/s-0037-1609019
Vethaak, A.D., Davies, I.M., Thain, J.E., Gubbins, M.C., Martínez-Gómez, C., Robinson, C.D., Moffat, C.F., Burgeot, T., Maes, T., Wosniok, W., Giltrap, M., Lang, T., Hylland, K. Integrated indicator framework and methodology for monitoring and assessment of hazardous substances and their effects in the marine environment. Marine Environmental Research 124, 11-20. DOI 10.1016/j.marenvres.2015.09.010
Gabriel, K.M.A, Kuechly, H.U., Falchi, F., Wosniok, W., Hölker, F. Resources of dark skies in German climatic health resorts Int J Biometeorol 61(1), 11-22. DOI 10.1007/s00484-016-1187-y
Kruse-Plass, M., Hofmann, F., Kuhn, U., Otto, M., Schlechtriemen, U., Schröder, B., Vögel, R., Wosniok, W. Reply to the EFSA (2016) on the relevance of recent publications (Hofmann et al. 2014, 2016) on environmental risk assessment and management of Bt.maize events (MON810, Bt11 and 1507) Environ Sci Eur (2017) 29:12. DOI 10.1186/s12302-017-0106-0
Haeckel, R., Wosniok, W., Gurr, E., Postma, T., Streichert, T. Quantity quotient reporting versus z-value for standardizing quantitative laboratory results J Lab Med 2017 41(2) 93–97
Haeckel, R., Wosniok, W., Arzideh, F., Zierk, J., Gurr, E., Streichert, T. Critical comments to a recent EFLM recommendation for the review of reference intervals Clin Chem Lab Med 55(3), 341–347. ISSN: 1434-6621. DOI: 10.1515/cclm-2016-1112
Schröder, W., Nickel, S., Schönrock, S., Schmalfuss, R., Wosniok, W., Meyer, M. et al. Bioindication and modelling of atmospheric deposition in forests enable exposure and effect monitoring at high spatial density across scales. DOI: 10.1007/s13595-017-0621-6.
Vethaak AD, Davies IM, Thain JE, Gubbins MC, Martínez-Gómez C, Robinson CD, Moffat CF, Burgeot T, Maes T, Wosniok W, Giltrap M, Lang T, Hylland K Integrated indicator framework and methodology for monitoring and assessment of hazardous substances and their effects in the marine environment. Marine Environmental Research, 124:11-20 (DOI: 10.1016/j.marenvres.2015.09.010)
Brückner M, Brannath W Sequential tests for non-proportional hazards data Lifetime Data Analysis, 23:339–352. DOI 10.1007/s10985-016-9360-5
Nitsche M, Brannath W, Brueckner M, Wagner D, Kaltenborn A, Temme N, Hermann RM Comparison of different contouring definitions of the rectum as organ at risk (OAR) and dose-volume parameters predicting rectal inflammation in radiotherapy of prostate cancer: which definition to use? British Journal of Radiology, 90(1070), Article No.\ 20160370
Brannath W Contribution to the discussion of “A critical evaluation of the current ‘p-value controversy’” Biometrical Journal, 59(5):875-876. DOI: 10.1002/bimj.201700034
Wullschleger, A., Wosniok, W., Timm, J., Heinze, M. Challenges and Perspectives in Bridging In- and Outpatient Sectors: The Implementation of Two Alternative Models of Care and Their Effect on the Average Length of Stay Psychiatry, 05 October 2017. DOI: 10.3389/fpsyt.2017.00196
Gutjahr G, Bornkamp B Likelihood Ratio Tests for a Dose-Response Effect using Multiple Nonlinear Regression Models. Biometrics, Journal of the International Biometric Society 73(1): 197-205. DOI:10.1111/biom.12563
Nickel S, Schröder W, Wosniok W, Harmens H, et al. Modelling and mapping heavy metal and nitrogen concentrations in moss in 2010 throughout Europe by applying Random Forests models Atmospheric Environment 156, 146–159. ISSN: 1352-2310. DOI: {10.1016/j.atmosenv.2017.02.032}
Dieckmann, K.-P., Radtke, A., Spiekermann, M., Balks, T., Matthies, Becker, C. P., Ruf, C., Oing, C., Oechsle, K., Bokemeyer, C., Hammel, J., Melchior, S., Wosniok, W., Belge, G. Serum Levels of MicroRNA miR-371a-3p: A Sensitive and Specific New Biomarker for Germ Cell Tumours European Urology 71(2), 213–220. ISSN: 0302-2838. DOI: 10.1016/j.eururo.2016.07.029
Dieckmann, K.-P., Radtke, A., Spiekermann, M., Balks, T., Matthies, Becker, C. P., Ruf, C., Oing, C., Oechsle, K., Bokemeyer, C., Hammel, J., Melchior, S., Wosniok, W., Belge, G. Serum Levels of MicroRNA miR-371a-3p: A Sensitive and Specific New Biomarker for Germ Cell Tumours European Urology 71(5), E161. ISSN: 0302-2838. DOI: 10.1016/j. eururo.2017.01.041
Year of publication: 2016
Authors Title Journal Link
Hoffmann, G., Lichtinghagen, R., Wosniok, W. Simple estimation of reference intervals from routine laboratory data J Lab Med 39(6) 389-402
Dieckmann K-P, Spiekermann M, Balks T, Ikogho R, Anheuser P, Wosniok W, Loening T, Bullerdiek J, Belge G A Novel Serum Biomarker of Testicular Germ Cell Tumors: Evidence for Specificity from Measurements in Testicular Vein Blood and in Neoplastic Hydrocele Fluid Urol Int. 97(1):76-83 (DOI: 10.1159/000444303)
Gabriel KMA, Kuechly HU, Falchi F, Wosniok W, Hölker F Resources of dark skies in German climatic health resorts Int J Biometeorol 61(1):11-22 (DOI 10.1007/s00484-016-1187-y)
Hofmann F, Kruse-Plass M, Kuhn U, Otto M, Schlechtriemen U, Schröder B, Vögel R, Wosniok W Accumulation and variability of maize pollen deposition on leaves of European Lepidoptera host plants and relation to release rates and deposition determined by standardised technical sampling Environ Sci Eur 28(1):14 (DOI 10.1186/s12302-016-0082-9)
Haeckel R, Wosniok W, Arzideh Equivalence limits of reference intervals for partitioning of population data. Relevant differences of reference limits LaboratoriumsMedizin 40(3): 199–205 (DOI 10.1515/labmed-2016-0002)
Haeckel R, Wosniok W, Gurr E, Peil B Supplements to a recent proposal for permissible uncertainty of measurements in laboratory medicine LaboratoriumsMedizin 40(2): 141–145
Hoffmann G, Lichtinghagen R, Wosniok W Simple estimation of reference intervals from routine laboratory data J Lab Med 39(6) 389-402
Lang T, Kruse R, Haarich M, Wosniok W Mercury species in dab (Limanda limanda) from the North Sea, Baltic Sea and Icelandic waters in relation to host-specific variables Marine Environmental Research 124:32-40
Schröder W, Nickel S, Schönrock S, Meyer M, Wosniok W, Harmens H, Frontasyeva MV, et al. Spatially valid data of atmospheric deposition of heavy metals and nitrogen derived by moss surveys for pollution risk assessments of ecosystems Environ Sci Pollut Res. 23(11):10457-76 (DOI:10.1007/s11356-016-6577-5)
Nitsche M, Brannath W Brückner M Wagner D Kaltenborn A,Temme N Hermann RM Comparison of different contouring definitions of the rectum as organ at risk (OAR) and dose-volume parameters predicting rectal inflammation in radiotherapy of prostate cancer: which definition to use The British Journal of Radiology . Epub ahead of print.
Wassmer G, Brannath W Group Sequential and Confirmatory Adaptive Designs in Clinical Trials Springer Series in Pharmaceutical Statistics, Springer, Swizerland
Hofmann, F., Kruse-Plass, M., Kuhn, U., Otto, M., Schlechtriemen, U., Schröder, B., Vögel, R., Wosniok, W. Accumulation and variability of maize pollen deposition on leaves of European Lepidoptera host plants and relation to release rates and deposition determined by standardised technical sampling. Environ Sci Eur (2016) 28:14. DOI 10.1186/s12302-016-0082-9
Kerkemeyer L, Wasem J, Neumann A, Brannath W, Mester B, Timm J, Wobrock T, Bartels C, Falkai P, Biermann J Effectiveness and cost-effectiveness of an integrated care program for schizophrenia: an analysis of routine data Eur Arch Psychiatry Clin Neurosci, 268(6):611-619 (doi: 10.1007/s00406-017-0830-x)
Zutt, M., Rudolph, H., Kaune, K.M., Wosniok, W., Gärtner, U., Linke, R. Myocardial scintigraphy – a method for detecting cardiac comorbidity in psoriasis patients? Journal of the German Society of Dermatology, DOI 10.1111/ddg.12892.
Graf A, Gutjahr G, Brannath W Precision of maximum likelihood estimation in adaptive designs Statistics in Medicine, 35(6): 922-941 (doi: 10.1002/sim.6761)
Haeckel, R., Wosniok, W., Gurr, E. and Peil, B. Supplements to a recent proposal for permissible uncertainty of measurements in laboratory medicine J Lab Med aop. http://dx.doi.org/10.1515/labmed-2015-0112
Dieckmann, K.-P., Spiekermann, M., Balks, T., Ikogho, R., Anheuser, P., Wosniok, W., Loening, T., Bullerdiek, J., Belge, G. MicroRNA miR-371a-3p – A Novel Serum Biomarker of Testicular Germ Cell Tumors: Evidence for Specificity from Measurements in Testicular Vein Blood and in Neoplastic Hydrocele Fluid Urol Int. DOI: 10.1159/000444303
Zutt M, Rudolph H, Kaune KM, Wosniok W, Gärtner U, Linke R Myocardial scintigraphy – a method for detecting cardiac comorbidity in psoriasis patients? Journal of the German Society of Dermatology, Journal of the German Society of Dermatology, epub ahead of print (DOI 10.1111/ddg.12892)
Schröder, W., Nickel, S., Schönrock, S., Meyer, M., Wosniok, W., Harmens, H., Frontasyeva, M.V, et al. Spatially valid data of atmospheric deposition of heavy metals and nitrogen derived by moss surveys for pollution risk assessments of ecosystems Environ Sci Pollut Res. doi:10.1007/s11356-016-6577-5
Haeckel, R., Wosniok, W., Arzideh, F. Equivalence limits of reference intervals for partitioning of population data. Relevant differences of reference limits LaboratoriumsMedizin 40 (3) 199–205, DOI 10.1515/labmed-2016-0002