Statistical-methodological research is conducted at the KKSB with emphasis on:

  • Adaptive designs
  • Application of EM algorithm in statistical computation
  • Bootstrap methods
  • Dose finding studies
  • Enrichment designs
  • Group-sequential designs
  • Mixture distributions
  • Modeling of censored and truncated data
  • Multiple testing, Informative simultaneous confidence intervals
  • Multivariate statistics
  • Non-parametric statistics
  • Patient-oriented randomization
  • Subgroup analyses
  • Survival-analysis and multi state models
  • Generalized linear models and their nonparametric extensions
  • Design of experiments, sampling design

The KKSB has experience with a large number of clinical trials and medical studies in a wide range of medical fields. These include for example:

  • Surgery
  • Diagnostic methods
  • Gynecology
  • Internal medicine
  • Laboratory medicine
  • Oncology
  • Ophthalmology
  • Orthopedics
  • Nursing sciences
  • Psychiatry
  • Radiology